SeraSeal ™ contains inert agar-polysaccharid/carbohydrate and clotting factors produced from bovine plasm (IIa, VIIa, IXa and Xa).
Agar, the complex sugar in SeraSeal ™, by application on the bleeding wound generates a cross linkage of fibrinogen/fibrin monomers and tissue proteins via the ions of the blood platelets‘ phospholipides and amine groups‘ cations and thus forms α-1,6-linked galactophosphorus and α-1,6-galactosamine by which a gelatine-like barrier on the wound is formed. This barrier reduces the escape of blood from the sore orifice, so that the fibrinous coagulation in the patient‘s cascade system can follow faster.
Covalent links of lysin and glutamine between gamma chains of adjacent fibrinous molecules and between adjacent alpha chains provide for coagulation stabilisation.
The clotting factors in SeraSeal ™ support the physiological coagulation cascade and work as catalysts in the formation of fibrine.
WHERE IS SERASEAL ™ USED?
CONTRAINDICATIONS / WARNING NOTICE
- SeraSeal ™ 1.5 ml vial
- SeraSeal ™ - 3 ml vial
- SeraSeal ™ - 5 ml vial
- SeraSeal ™ 11 cm "atomizer" spray catheter
- SeraSeal ™ 22 cm "atomizer" spray catheter
- SeraSeal ™ 36 cm laparoscopy-KIT
- SeraSeal ™ 230 cm colonoscopy-KIT
- SeraSeal ™ 120 cm bronchoscopy-KIT
STORAGE / DURABILITY
Short-term storage (up to 10 days) at low fridge temperatures (from +2°C to +8°C).
For short periods (up to 24 hours) the product can be kept and used at room temperature.
After thawing, SeraSeal ™ can be stored again at minus 10°C. Deep frozen SeraSeal ™ has a high durability of 36 months.